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Topigen (Topiramate)
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Topiramate

Topigen is used alone or with other medications to treat certain types of seizures including primary generalized tonic-clonic seizures (formerly known as a grand mal seizure; seizure that involves the entire body) and partial onset seizures (seizures that involve only one part of the brain). Topigen is also used with other medications to control seizures in people who have Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). Topigen is also used to prevent migraine headaches but not to relieve the pain of migraine headaches when they occur. Topigen is in a class of medications called anticonvulsants. It works by decreasing abnormal excitement in the brain.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Compression stockings may represent a therapeutic option to elevate leg Plp and ameliorate leg edema, thereby leading to improved quality of life in healthy females with low leg Plp. Early childhood social disadvantage is associated with poor health behaviours in adulthood.

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Evaluation of the adsorptive behavior of cesium and strontium on hydroxyapatite and zeolite for decontamination of radioactive substances. The aim of the study was to determine the oral health status of children with asthma and to evaluate the oral health parameters according to the medications and severity of the disease.

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Effect of intravenous esomeprazole 40 mg and pantoprazole 40 mg on intragastric pH in healthy subjects. BiFC analysis was used to investigate interactions among bZIP and Rel family transcription factors. It is important to remember that the hypotensive effect of ACE inhibitor is augmented in patients on a thiazide diuretic. MitoSeek can be set up to run in parallel or serial on large exome sequencing datasets.

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Our findings suggest that at follow-up at 24 months the LARS ligament seems to be a satisfactory treatment option, especially when an early return to high levels of activity is demanded. Importance of long term resting heart rate in the development of cardiomegaly. The five studies demonstrated statistically significant reduction in medication errors in patients with renal insufficiency, pregnant women dispensed US Food Drug and Administration (FDA) risk category D (evidence of fetal risk but therapeutic benefits can outweigh the risk) or X (evidence suggests that risk to the fetus outweighs therapeutic benefits) medication, first dispensing of inappropriate medications in patients aged 65 and above, co-dispensing of interacting drugs, and adverse drug events related to hyperkalaemia.

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Because of its high soft-tissue contrast, Magnetic Resonance Imaging (MRI) is used increasingly for guidance and control of minimal invasive and neurological surgical procedures. However, the interaction between p75(NTR) and TrkA receptors required for this activity is not understood.

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Neuropeptide Y: some viewpoints on a multifaceted peptide in the normal and diseased nervous system. Anti-CD45 radioimmunotherapy using (211)At with bone marrow transplantation prolongs survival in a disseminated murine leukemia model. Treatment reality in elderly patients with advanced ovarian cancer: a prospective analysis of the OVCAD consortium.

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Self rated health as a predictor of coronary heart disease in Copenhagen, Denmark. We suggest that our results support an association between negative parenting and adolescent functioning, which may be mediated by immature or delayed brain maturation.

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To examine this assumption, we alternately repeated short and rapid fore- and backfiltrations (push/pull HDF) through a protein-permeable membrane, each less than 1 second in duration and at each filtration volume of 15 ml, where a pyrogen-free dialysate was supplied. VLPL were isolated from human vaginal mucosa by enzymatic techniques. Isolation of peroxisome subpopulations from rat liver by means of immune free-flow electrophoresis.

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For all samples, starch fractions which escaped digestion in the small intestine were composed of three populations of alpha-glucans with proportions differing according to the substrate. Identification of the chondrogenic pathway in the mandibular condylar cartilage. A 48-year-old patient with Marfan syndrome presented with an ascending aortic and arch periprosthesis hematoma (14.0 x 9.0 cm) and a descending aortic aneurysm (8.7 x 9.1 cm) developed over the last 2.5 years, after several operations on the ascending aorta and arch as well as stent-graft placement in the descending aorta. Performance of the Wisconsin Card Sorting Test (WCST) and related brain-activation patterns reflect both task learning and execution. Use of the MMPI-2 in the outpatient assessment of women with Anorexia Nervosa or Bulimia Nervosa.

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Comparison of Contrast-Enhanced Multiphase Renal Protocol CT Versus MRI for Diagnosis of Papillary Renal Cell Carcinoma. There is growing evidence that antimicrobial prophylaxis is also beneficial in cases with preoperatively sterile urine. Schiff bases of pyridoxal phosphate with active center lysines of ribonuclease A.

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Performance-based measures such as the CS-PFP10 may provide additional insights into physical function in patients with HF that more commonly used exercise tests may not identify. These findings may allow for better characterization of pathologies and eventually assist in improving the clinical utility of DKG.

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During 1992, 1993 and 1994 a total of 65, 123 and 142 faecal samples respectively yielded 9, 54 and 87 strains of V. A qualitative method using interviews was conducted and the data material was analysed according to manifest and latent content analysis. Each article was reviewed by two independent investigators with discrepancies resolved by consensus.

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We demonstrate that GABA(B)R subunits are segregated and differentially mobile in dendritic intracellular compartments and that a high proportion of non-associated intracellular subunits exist in the brain. Duplicate exstrophy of the bladder is a rare, distinct congenital anomaly without additional major anomalies of the urinary tract.

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Efficient, Edge-Aware, Combined Color Quantization and Dithering. This paper describes a simple direct semiparametric procedure to incorporate population-wide information from as many individuals as required to support analysis of data on any specific individual. We established a highly sensitive electrochemiluminescence (ECL)-based assay to measure CSF antibody reactivity against purified myelin particles and biotin anchored liposomes. Intent-to-adhere and adherence to malaria prevention recommendations in two travel clinics.

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These were randomly divided into two groups, group A and group B. We have utilized a comprehensive and sensitive array-based DNA mapping technique, the methylated-CpG island recovery assay, to profile the DNA methylation pattern in ductal carcinoma in situ. In this review, selected nanotechnologies under development for early detection of atherosclerotic disease and identification of vulnerable plaques are presented. These phytoplankton functional groups varied significantly, both seasonally and longitudinally.

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Turning to complex structures, we reveal that the bandgap opening in ZH-GALs results mainly from the intervalley scattering. Current Neural and Behavioral Dimensional Constructs across Mood Disorders. This approach negates the possibility that multiple co-occurring, and seemingly contrasting, behaviors may manifest within the same individual.

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A major concern in these systems is radiofrequency-induced tissue heating, which can be avoided by specific absorption rate (SAR) prediction and SAR monitoring before and during the scan. A controlled trial comparing combination therapy with ofloxacin (OFLX) and interferon (IFN) versus IFN monotherapy was conducted in patients with chronic hepatitis C who failed IFN therapy. We use the immersed boundary method to couple microbial motion and the advection-diffusion of substrate with the full incompressible Navier-Stokes equations. Although macrolide antibiotics (macrolides) provide anti-inflammatory effects, these effects have not been well studied in influenza patients.

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Deletion of the core-H region in mice abolishes the expression of three proximal odorant receptor genes in cis. We compare the performance of a commercially available digital fluoroscopy system with conventional film-screen combinations in gastrointestinal barium studies. When applied to these health attributes, commonly used biased estimation techniques can lead to false conclusions and ineffective disease intervention and control. Clinicopathologic data available on 10 horses included hypocalcemia, hypomagnesemia, and azotemia.

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Steady-state kinetic parameters comparing the two Dol-PP-OS to a shorter dolichylpyrophosphate disaccharide (DolPP-DS) previously synthesized in our laboratory are reported. We developed, implemented and evaluated an evidence-based programme of feedback designed to address limitations identified in the current literature. We explain the robust features of the model by the adjustable dynamics of its global loading-unloading cycle, which allows maintaining the long-term stationary state without affecting the intrinsic avalanche dynamics.

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Adverse Events in Treating Smear-Positive Tuberculosis Patients in China. Children in regular or integrated education scored higher on verbal, reasoning and school-achievement tests. Ammonium sulfate fractions of broth culture filtrates were dialyzed, concentrated by lyophilization, and tested for toxic effects by mouse intraperitoneal injection. This approach allows the unambiguous assignment of specific biotransformations to specific enzymes.

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Liver vitamin A storage was 4.5 times higher in rats supplemented with vitamin E than in rats without any supplement, but the effect of excess dietary vitamin E was no different from that of normal level (25 IU/kg diet). The diagnosis was primary retroperitoneal GIST (gastrointestinal stromal tumor). In exceptional cases, trigeminal neuralgia may present in infancy and be the only manifestation of a Chiari malformation. Evolution of the hemopoietic stem cell population in isogenic radiochimeras

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Nurses in wards with HCAs performed significantly fewer activities than nurses in control wards. We demonstrate that overexpression of the constitutively active Ras-V12 induces senescence in primary human keratinocyte cultures, but that some cells escape senescence and proliferate indefinitely. Lack of association of a polymorphism in the low-density lipoprotein receptor-related protein gene with Alzheimer disease. CEA positivity in tissue and sera of patients with benign breast lesions. To indicate their particular dual function, CPSNs are proposed to be termed secreto-sensory nociceptive neurones.

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There were performed experimental study on the effect of Al(OH)3, 16,16dmPGE2, indomethacin, verapamil and calcium ionophore A 23157 on alcohol-induced injury of isolated gastric mucosal cells of rat. History and clinical examination, fluorescein angiography, optical coherence tomography, autofluorescence, electrophysiology, and genetics.

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Responses of embryonic and larval inland silversides, Menidia beryllina, to a water-soluble fraction formed during biodegradation of artificially weathered Alaska North Slope crude oil. We performed a case study and intervention study, with follow-up of 1 to 5 years, in 4 children with inner ear malformations who underwent implantation of a multichannel cochlear implant (Nucleus, Cochlear Corporation) at ages 3 to 12 years. Professional Practice advocacy: a multipurpose approach to chaos in the health care system.

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Hearing loss accelerates brain function decline in older adults. Activation of herpes specific antigens and infectious virus in a hamster cell line transformed by HSV-2. Antifactor Xa levels in critically ill Korean patients receiving enoxaparin for thromboprophylaxis: a prospective observational study. Some common North American aguatic snails as experimental hosts of Angiostrongylus cantonensis--with special reference to Lymnaea palustris.

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Three-dimensional CT diagnosis of myositis ossificans of the sacrospinous ligament. However, whether antithrombotic therapy prevents recurrent miscarriage in thrombophilic women, or in women with severe pregnancy complications, remains unknown and urgently requires future research. This finding suggests that this factor accounts for the in vitro and in vivo difference in the tumor disposition of MRK16. While the clinical benefits of specialist equipment and IT are appreciated, questions remain as to whether the investment is cost-effective, and how specialist equipment and IT may be used to best advantage in community optometric practice.

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Natriuretic peptide (NP) deficiency and sustained renin-angiotensin system activation are associated with impaired oxidative metabolism and predispose to type-2 diabetes. Patient age had no statistically significant effect on refraction and corneal haze 1 year after PRK. Spontaneous epistaxis refractory to sphenopalatine artery closure is to be addressed externally, preferably under endoscopic vision. Improved in vitro stability of serum osteocalcin by using a new commercially available antiproteolytic compound. There were no differences between the two CPB groups in blood loss or transfusion requirements.

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It is well-documented and accepted as an explanation for unusual patterns of tumor recurrence at multiple sites in the body. High arched palate is also a prevalent feature of fibroblast growth factor (FGF) hyperactivation syndromes. BCG-induced protection in guinea pigs vaccinated and challenged via the respiratory route. Narrow-band resonance-ionization and fluorescence imaging in a mercury-vapor cell.

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AVX-470 is an oral, polyclonal bovine-derived anti-tumour necrosis factor (TNF) antibody in development for treatment of inflammatory bowel disease (IBD). The unique character of GT development and the sexual dimorphism are discussed.

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The reporter plasmid contains a second reporter gene, which is constitutively expressed and hence eliminates the requirement of a second plasmid used as a transformation control. The qualitative and quantitative differences in adsorption of the CVB3 strains to two human fibroblast lines as well as to HeLa cells corresponded well with the virological results. However, some strains showed cross-reactivity, especially, many type II strains reacted with type III antisera. The method can be applied to the quality control and studies on chemical constituents of Radix Astragali.

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Differences in the physicochemical properties of HP-PSA and HP-OA which originate from differences in the double bond position most likely determine the efficacy of these compounds as skin penetration enhancers. Mapping of Membrane Lipid Order in Root Apex Zones of Arabidopsis thaliana.

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In diabetic mice, mGLP-1 displayed a significantly improved glucose-lowering activity as judged by fasting glucose and insulin, oral glucose tolerance test, beta cell function analysis and histochemical analysis. Such ntES cells can be used not only for experimental models of human therapeutic cloning but also as a means of preserving mouse genomes instead of preserving germ cells. Repeated doppler flow imaging showed thrombus resolution within 3 weeks.

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Arteriovenous fistula obstruction and expression of platelet receptors for von Willebrand factor and for fibrinogen (glycoproteins GPib and GPiib/iiia) in hemodialysis patients. Prospective studies are warranted to assess the validity of the CPE score.

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There are two pollutants of particular concern and that both pose challenges for risk assessment and policy, and they are particulate matter (PM) and ozone. Given its available genetic resources, numerous, easily accessible natural populations, and patterns of genetic variation highlighted in this research, M. From April to May 2005, all stools submitted for CDTA were also cultured for VRE using vancomycin containing culture media.

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Differences in the response of serum lipoproteins to fenofibrate between women and men with primary hypercholesterolaemia. Therapy with atovaquone for Cryptosporidium parvum infection in neonatal severe combined immunodeficiency mice. In this article, the authors review the anatomic, diagnostic, and management considerations as well as discuss their own experience in approaching nasal trauma and the deviated nose. Matrix metalloproteinase (MMP) and TGF beta 1-stimulated cell migration in skin and cornea wound healing.

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Our data show that MAP kinase cascade activation is an early event following the reappearance of v-mos expression and v-mos kinase activity upon temperature shift, while the first manifestation of morphological transformation appears 24 h after the shift to permissive temperature. The gastrointestinal organs and the kidney have a major role in the absorption, metabolism and excretion of analgesics and changes in their function predispose individuals to adverse effects. A retrospective review was made of all the lesions surgically treated in our hospital. This study was designed to elucidate the effects of hypertension and aging on nitric oxide (NO)-mediated relaxation response to acetylcholine in the rat aorta.

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MiR-451 was reported to relate to the development of lung cancer and metastasis of glioma. A case of hepatic hernia with echocardiographic findings simulating right atrial tumor. Because of heart-lung interactions, weaning from mechanical ventilation induces strong hemodynamic changes that can lead to weaning-induced cardiac failure. Cord arterial lipid peroxide concentrations and acid base balance were determined at delivery.

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The corticotropin-releasing factor (CRF) family is also known to regulate energy balance. These data highlight that the FGF2/p65/miR-105/Runx2/ADAMTS axis might play an important role in OA pathogenesis and that miR-105 might be a potential diagnostic target and useful strategy for OA treatment.

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Properties of Boolean dynamics by node classification using feedback loops in a network. Endothelial-dependent dilator function was merck manuals omeprazole dosage determined by the topical application of acetylcholine (ACh). Evaluation of an ELISA assay for total proinsulin and establishment of reference values during an oral glucose tolerance test in a healthy population. REFLECTIONS APROPOS OF AN ETIOPATHOGENIC STUDY OF A GROUP OF 225 CHILDREN WITH SEVERE, MODERATE AND SCHIZOPHRENIC MENTAL DEFICIENCY

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This study aimed to study the prevalence of G6PDd and its janacin norfloxacin 400mg for diarrhea association with malaria occurrence in the Brazilian Amazon. Aberrant Mer receptor tyrosine kinase expression contributes to leukemogenesis in acute myeloid leukemia. Organizations interested in partnering with congregations to promote health or prevent HIV should consider congregational size as well as other factors that predict involvement. Outcome analysis of arthroscopic treatment of partial thickness rotator cuff tears.

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