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Abalam (Abacavir)
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Abacavir

Abalam is an oral medication that is used for the treatment of infections with the human immunodeficiency virus (HIV). It is in a class of drugs called reverse transcriptase inhibitors which also includes zalcitabine (Hivid), zidovudine (Retrovir), didanosine (Videx), lamivudine (Epivir), emtricitabine (Emtriva), and stavudine (Zerit). During infection with HIV, the HIV virus multiplies within the body's cells. The newly-formed viruses then are released from the cells and spread throughout the body where they infect other cells. In this manner, the infection continually spreads to new, uninfected cells that the body is continually producing, and HIV infection is perpetuated. When producing new viruses, the HIV virus must manufacture new DNA for each virus. Reverse transcriptase is the enzyme that the virus uses to form this new DNA. Specifically, Abalam is converted within the body to its active form (carbovir triphosphate). This active form is similar to a compound (deoxyguanosine triphosphate), a chemical that is required by the HIV virus to make new DNA. The reverse transcriptase uses carbovir triphosphate instead of deoxyguanosine triphosphate for making DNA, and it is the carbovir triphosphate that interferes with the reverse transcriptase. Abalam does not kill existing HIV virus, and it is not a cure for HIV. The FDA approved Abalam in December 1998.

Other names for this medication:
Abacavir, Abalam, Epzicom, Kivexa, Abamune, Virol, Ziagen,

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The comparative cellular architecture of the female gonoduct among tylenchoidea (nematoda: tylenchina). Retrospective chart review of 38 patients with head and neck cancer and N2/N3 neck disease who were treated with chemoradiation and who had an MRI 6 to 8 weeks following treatment. Recent studies have indicated that sense of SE and effective coping strategies (CSs) are the crux on which the management of chronic pain and enrichment of QoL of FMS patients depend. From August 2004 to December 2007, 106 cases of transverse colon cancer were managed by resection at our institution, and 89 of these cases were included in this study.

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Structure-activity relationship of a series of synthetic lipopeptide self-adjuvanting group a streptococcal vaccine candidates. Under the optimal conditions, the linear ranges of uric acid and ascorbic acid were both from 25 to 600 microM, with the correlation coefficients of 0.997 and 0.996, respectively. This suggests a higher than average loss in activity in these towns. Introduction to scintillation scanning and radiopharmaceuticals. Further analysis by means of a CT scan revealed severe tracheal compression and active bleeding, which prompted immediate operative intervention.

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Apoptosis rates were significantly different with that of control group. When FFPE cell blocks could not be prepared or prepared unsuccessfully from the cytologic specimens, qRT-PCR may be an alternative option for the detection of ALK gene fusion. We report two cases of hyperinfection strongyloidiasis in renal transplant recipients and document endoscopic and pathological changes in the involved small bowel.

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Displacement thresholds were measured in eighty subjects in the 18-85-yr age range. Simultaneous Determination of Metamizole, Thiamin and Pyridoxin Using UV-Spectroscopy in Combination with Multivariate Calibration. Changes in pharmacodynamics and pharmacokinetics of psycholeptic drugs in the course of radiation disease. MTX has many serious adverse effects, such as myelosuppression, hepatic, renal and pulmonary disorders.

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In addition, we report specific protein sequence motifs enriched in Kme1 sites that are directly regulated by endogenous SMYD2 activity, revealing that SMYD2 substrate specificity is more diverse than expected. TMC310911, a novel human immunodeficiency virus type 1 protease inhibitor, shows in vitro an improved resistance profile and higher genetic barrier to resistance compared with current protease inhibitors. Prematurely born infants can develop the neonatal respiratory distress syndrome (RDS) because of a deficiency of pulmonary surfactant.

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In spring 1993, a cohort of 1,468 patients with chronic artery disease was identified using claims data. The hypothalamic mammillary region is critical for spatial memory and vestibular processing. Exquisite control of the level and activity of p53 are required in order to preserve cellular homeostasis following DNA damage. The percentage of stroke hospitalizations resulting in death decreased over the last decade likely reflecting advancements in acute stroke care.

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These studies provided important insight into transcriptional control mechanisms during T cell development and into the regulation of cis-regulatory networks in general. Comparison of 3 different analytic approaches for determining risk-related active and sedentary behavioral patterns in adolescents. Repeated intra-articular injections of acidic saline produce long-lasting joint pain and widespread hyperalgesia. An assessment model: a systemic examination of the psychosocial needs of patients with epilepsy.

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The news media provide significant health information to the American public. Changes in platelet function and susceptibility of lipoproteins to oxidation associated with administration of aged garlic extract. The results are obtained for the broad band control design based on the formulation for discrete frequency control. In vivo and in vitro effects of beta-endorphin on glucose metabolism in the rat. Stimuli were presented in which a moving object (A) contacted a stationary object (B), whereupon both objects moved back in the direction from which object A had come.

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Cranial CT showed supratentorial multiple cranial metastases and peritumoral oedema. Calcification and eventual integration of orthopedic implants into bone is important to many load-bearing devices, and the influence of load and implant stiffness on this process are assessed in this mathematical modelling study. SF-12 physical component score (PCS-12) and mental component score (MCS-12) were derived using the standard US algorithm. It presents as multiple purple and red papules and nodules on the head and neck or the extremities. Uncertainty remains about the extent and indications for inguinal lymphadenectomy in penile cancer, a procedure known for relatively high morbidity.

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The concentration of ACBP and FABP was increased in peroxisome proliferator-treated hepatocytes relative to vehicle controls within 48 h of treatment. The transcriptome of embryos produced in serum-free conditions showed a greater resemblance to that of in vivo derived embryos, although genes involved in lipid metabolism were altered. A novel case of an adenomyosis-related uterine rupture in pregnancy. Crystal growth simulations of methane hydrates in the presence of silica surfaces.

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In such cases the combination of the two treatment modalities are commonly used. The present study aims to clarify the role of surgery in psychopathologic alterations.

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Secondary ischemic insults are common after severe head injury and contribute to poor neurological outcome. Violence behaviors are instances of workplace maltreatment that damage individual nurses, quality of care, and the ethical climate of the healthcare settings. Human immunodeficiency virus (HIV) in the asymptomatic phase of the infection impairs some aspects of cognition, but little is known about how visuospatial functions are affected. We expected that higher cognitive function would be associated with better adherence to postoperative guidelines.

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However, current evidence of telerehabilitation measures in neurological patients is scarce in our country, so is necessary a larger number of studies focusing on the validity, reliability, effectiveness and efficiency of the technique. Nitrogen transport and transformation in the saturated-unsaturated zone under recharge, runoff, and discharge conditions. MetO reduction is catalyzed by specialized enzymes, termed methionine sulfoxide reductases (MSRs), involved in senescence and protection against diseases and environmental constraints. The mechanism of dextrin interaction with the surface metal hydroxy sites, ( identical withMeOH), was found to proceed via chemical complexation.

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Such devices may improve patient compliance and serve as a means of extended delivery of antiglaucoma medications. The present data demonstrates the potential of azvudine as a complementary drug to current anti-HIV drugs. Subjectivity and sexuality production in women living with HIV/aids: a sociopoetic production. The objective of this study was to examine whether the combination of intravenous PGF2 alpha and inhaled NO in ARDS lungs has a beneficial effect on oxygenation.

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Polymorphism rs2274911 of GPRC6A as a Novel Risk Factor for Testis Failure. Eradication rates, risk factors, and implant selection in two-stage revision knee arthroplasty: a mid-term follow-up study. This observation is supported by results from subcellular-fractionation experiments. Quantitative differential proteome analysis in an animal model for human melanoma. Clinical characteristics of certain forms of so-called fatal delirium

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Both a commercial naphthenic acid and a naphthenic acid extract prepared from OSPW had similar fluorescent spectra with peaks at 280 nm and 320 nm and minor shoulders at approximately 303 and 331 nm. Characteristics of monoamine oxidase activity in brain and other organs of the adult bullfrog, Rana catesbeiana. Recent advances in ultrasound technology have increased the consistency, safety, and ease of a caudal block even in older patients. A major challenge in the management of nonalcoholic fatty liver disease (NAFLD) is to identify patients with nonalcoholic steatohepatitis (NASH) and early liver fibrosis. The mechanism and significance of the slow changes of ventricular action potential duration following a change of heart rate.

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Eldecalcitol: a review of its use in the treatment of osteoporosis. Most cases of infection are sporadic, however, and the contribution of food vehicles, animal contact, and person to person spread in the acquisition of infection needs to be clarified. In 2003, the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure recognized sleep apnea as a common and identifiable cause of hypertension and suggested blood pressure screening among patients with OSA. Owing to its mode of action and pharmacological effects, almitrine bismesylate corrects the main physiopathological disorders underlying hypoxaemia and its complications in chronic bronchitis.

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Better results, including cure, may be expected when a MERF is caused by lymphoma. The differences vary also between countries according to their welfare regime and their social policy. Cervical cancer, although less common in industrialized countries, is the fourth most common cancer affecting women worldwide and the fourth leading cause of cancer death. Intermittent drawn ribbons of polymer with oriented crystals were observed in both scanning electron microscopy and atomic force microscopy.

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Most penetrating needle puncture injuries occur in retro- or peribulbar anesthesia. Comparison and contrast of the biological effects of carbamazepine with classical treatment agents, such as lithium carbonate, tricyclic antidepressants, and neuroleptics may help elucidate mechanisms underlying the pathophysiology of the mood disorders.

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Specificity of tests for the detection of early obstruction of the airways CPLI should be measured in cases of canine IBD as elevated CPLI was associated with a worse outcome.

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Selected adipokines - plasma concentrations and adipose tissue expressions during 24-hour lipid infusion in healthy men. Comparison with the databases of all known human SAGE tags allowed us to identify a number of keratinocyte-specific tags that putatively correspond to formerly unknown genes. Since the electrochemical gradient for K is directed out of the cell there is no need to invoke active processes to explain RVD. Multi-objective evolutionary algorithms (MOEAs) have become increasingly popular as multi-objective problem solving techniques.

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Haematological and haemopoietic studies in an air-breathing fish on cyanocobalamin and folacin deficient diet. Reasons for declining kidney donors are older age, with or without, hypertension, kidney dysfunction, and diabetes.

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The number of patients receiving repeat prescription for supplements in each area between 2004 and 2011 was analysed. A NEW HEMOFLAGELLATE (GENUS CRYPTOBIA) FROM MARINE FISHES OF NORTHERN NEW ENGLAND. BSP computed from this representative burst suppression pattern may be more resilient to noise and a better representation of the brain state of patients. The aim of this article is to demonstrate the importance of the role a health CRM can play in a pandemic or health alert. The new information may help inform clinicians and parents making difficult decisions about genital surgery for infants with ambiguous genitalia.

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Perspectives on the renin-angiotensin-aldosterone system in hypertension. The house dust mite, Euroglyphus maynei (EM), is common in homes in England, Europe, the southern United States, and other parts of the world. Antitumor Properties of an IgG2-Enhanced Next-Generation MET Monoclonal Antibody That Degrades Wild-Type and Mutant MET Receptors. In addition, this willingness to participate changed to the same extent for both increasing out-of-pocket costs and increasing financial rewards.

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We present here the proteomic identification of 101 CrkL-SH3 binding proteins from embryonic murine brain. Oxidative stress, brain white matter damage and intrauterine asphyxia in fetal lambs.

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Electrophoretic mobility shift assays showed that nuclear extracts from overexpressing clones gave a different pattern of protein-DNA binding to an AP-1 consensus oligonucleotide compared to wild-type cells. The nonlinear pulse propagation is analyzed using two complementary theoretical approaches.

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The protective and restorative potentials of resveratrol on endothelium-dependent relaxations were evaluated in hypercholesterolemic rabbit corpus cavernosum (CC). The hard and soft tissue changes were more related in the horizontal and anteroposterior aspects than in the vertical one. Monoclonal antibody against Babesia equi: characterization and potential application of antigen for serodiagnosis.

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Our results indicate that CTL precursors to the PAP gene product exist and could be potentially recruited to elicit an antitumor response. Changes in volatile aroma compounds of organic fragrant rice during storage under different conditions. Judicious manipulation of preferred target sequences of pyrimidine-specific ribonucleases may be useful in designing effective hammerhead ribozymes. Measures included sexual orientation, military sexual trauma, mental and gender-specific health diagnoses, and VA healthcare utilization and satisfaction.

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PGE2 was applied to the cornea for 4 min with the use of a glass cylinder in pigmented rabbits. Immunohistochemistry was performed for ER, PR, Her-2/neu and p-53. The result of chemical modification revealed that binding of FMN to the aptamer domain induced the helix formation in stem II required for catalytic activity. Cyclosporine A neurotoxicity in a patient with idiopathic renal magnesium wasting.

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Anxiety and depression scores showed a decreasing trend in the TTM group. A 19-month-old child developed the nephrotic syndrome coincident with an Epstein-Barr virus (EBV) infection.

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In particular, CD8 cytotoxic T lymphocytes (CTLs) play a central role. The double- and triple-lesioned rats also had more stable sleep architecture compared with nonlesioned saline rats. In this case, the bacterial regrowth is usually accompanied by concomitant increase in the tissue levels of IL-10 and transforming growth factor-beta (TGF-beta), well known immunosuppressive cytokines. Two of them are modified at pH8,0 within 30 min and are both found in the peptide, which has been demonstrated to contain the most reactive cysteine residue.

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We recorded DRN neurons from rats in a contextual conditioned approach paradigm in which an auditory cue was either followed or not followed by reward, depending on a global context signal. A phenotype is analyzed by immunohistochemistry techniques, and a genotype is clarified by various gene chromosome tests. ANG-II did not cause sustained vasoconstriction, but induced inward remodeling dependent on presence of myogenic tone pegasys copegus price and tyrosine phosphorylation. Parental communication, readiness of adolescents to leave home, and the course of treatment.

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This study aimed to determine differences in the proximal femur morphology of elderly patients with femoral neck fractures among the ethnic groups in Singapore. Orbital apex syndrome associated with fractures of the inferomedial orbital wall. At present, we are studying 67 different meningococcal isolates collected miracid dosage form abbreviations from all parts of Norway during the MenOPP project.

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