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A total of 90 parent-offspring trios recruited in Denmark and France were investigated using the transmission disequilibrium test (TDT). To determine whether controlled changes in barometric pressure activate rat spinal trigeminal neurons as a possible animal correlate of headaches. Downstream of tyrosine kinase/docking protein 6, as a novel substrate of tropomyosin-related kinase C receptor, is involved in neurotrophin 3-mediated neurite outgrowth in mouse cortex neurons. Prospective clinical pilot trial in a single cohort group of rhPDGF in foot arthrodeses. Here we compared blink related artifacts in non-invasive and invasive EEG, simultaneously recorded from prefrontal and motor cortical regions using an approach suitable for detection of small artifact contamination.

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The findings raise questions regarding the statistical validity and reliability of assessments currently used in clinical practice. To examine the pattern of the metabolic syndrome in Chinese and the causal relationships among its components, including aging, obesity, hyperglycemia, hypertension, hypertriglyceridemia, and hyperinsulinemia in these subjects. In 1985, geographic factors made a dramatic contribution to hormone-dependent tumors incidence while economic ones--to that of gastrointestinal neoplasms. Evidence based medicine consists in systematically finding, appraising and using validated research results as a basis for clinical decision making. Enemies and brothers in arms: Candida albicans and gram-positive bacteria.

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The development of a series of biarylphosphine ligands has led to the identification of an improved catalyst for the coupling of electron-deficient heterocyclic substrates. Transversal studies showed that mixed acinar-ductal tumours could be identified by FDG PET several weeks before they could be detected by hand palpation.

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Annual vaccination is the most effective means to prevent or attenuate this illness. To investigate the relationship between endogenous androgens and body fat distribution in early and late postmenopausal women. Preoperative preparation of mice and rats, suitable anaesthesia, and postoperative treatment and pain management are described in detail. CNVs detected were categorized into syndrom related CNVs, recurrent CNVs and rare CNVs.

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In addition to lipid second messengers derived from the plasma membrane, increasing evidence supports the existence of nuclear lipid-dependent signaling networks. This retrospective study evaluated the efficacy and toxicity of trastuzumab and paclitaxel plus capecitabine in the first-line therapy for patients with HER2-positive MBC.

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We demonstrate that clofibric acid (CA) enhances the response of HL60 cells to all-trans RA and D3. In 2011 our group published structures of the Caenorhabditis elegans glutamate-gated chloride channel (GluCl) in complex with the allosteric partial agonist ivermectin, which provided insights into the structure of a possibly open state of a eukaryotic Cys-loop receptor, the basis for anion selectivity and channel block, and the mechanism by which ivermectin and related molecules stabilize the open state and potentiate neurotransmitter binding. The vaccinia virus 42-kDa envelope protein is required for the envelopment and egress of extracellular virus and for virus virulence.

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Oral lesions, especially when accompanied by esophageal symptoms, were sufficient for diagnosis. Behavioral treatment approaches show significant promise for treating drug-abusing adolescents, but many have not incorporated innovations in neuroscience on brain development, cognitive processes, and neuroimaging.

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Inhibition of DNA polymerases from RNA tumor viruses by tilorone and congeners: site of action. In plants, multistep component systems play important roles in signal transduction in response to environmental stimuli and plant growth regulators. Liquid Raman and infrared spectra in liquid and gaseous state measurements revealed the presence of two conformations anti, anti (Cs symmetry) and anti, gauche (C1 symmetry).

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