Ceftum axetil is an orally active prodrug of Ceftum. After oral administration, Ceftum axetil, as Ceftum, is absorbed from the gastrointestinal tract and rapidly hydrolyzed by nonspecific esterases in the intestinal mucosa and blood to release Ceftum into the blood stream. Conversion to Ceftum, the microbiologically active form, occurs rapidly. The inherent properties of Ceftum are unaltered after its administration as Ceftum axetil. Ceftum exerts its bactericidal effect by binding to an enzyme or enzymes referred to as penicillin-binding proteins (PBPs) involved in bacterial cell wall synthesis. This binding results in inhibition of bacterial cell wall synthesis and subsequent cell death. Specifically, Ceftum shows high affinity for PBP 3, a primary target for Ceftum in gram-negative organisms such as E. coli.
Other names for this medication:
Cefuroxime,
Ceftum,
Zocef,
Cefakind,
Supacef,
Altacef,
Oratil,
Stafcure,
Pulmocef,
Zefu,
Ceftin,
Kefurox,
Zinacef,
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Monolitum,
Zitrocin,
Gatilox,
Metsec,
Alizar,
Gastrodine,
Stomex,
Aklovir,
Penmox,
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Lansomid,
Cyclovir,
Voxin,
Sobelin,
Gastrolan,
Antidep,
Anten,
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Sereupin,
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