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Clovate (Acyclovir)

Clovate is an antiviral drug, a synthetic nucleoside analogue, that has inhibitory activity (interferes with viral replication) against the herpes viruses, including herpes simplex 1 and 2 (cold sores and genital herpes), varicella-zoster (shingles and chickenpox), and Epstein-Barr virus (mononucleosis). Viruses take over living cells and reproduce themselves, often at the expense of the host cell. The Clovate is converted to an active form by the virus itself, and the virus then uses the active form of Clovate rather than the nucleoside it normally uses to manufacture DNA, a critical component of viral replication. Incorporation of active Clovate into new viral DNA stops the production of the DNA. Virally infected cells absorb more Clovate than normal cells and convert more of it to the active form, which prolongs its antiviral activity. The FDA approved Clovate in March 1982.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

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Ten pathologists with varied experience in interpretating p16 immunostains evaluated each slide independently. Children of farm laborers: utilization of services for mental health problems. Upon spermidine binding, the Vmax value of the enzyme was increased and the kcat/Km values were enhanced slightly. Amendment to the welfare law with regard to care of speech disorders and more severe cases of alexia

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Differential regulation of ERK1/2 and p38 MAP kinases in VacA-induced apoptosis of gastric epithelial cells. The isolation of pathogenic strains of Yersinia enterocolitica from food and water samples by culture is time-consuming and unreliable.

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However, no published data is available regarding the combined pharmacokinetics and bioavailability of this particular fixed dose combination. Vaccines, virucides and drugs against HIV/AIDS: hopes and optimisms for the future.

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A Giant Hydronephrosis Mistakenly Diagnosed as Ovarian Tumor in a Pregnant Woman. As a prerequisite for development of improved vaccines and diagnostic tools for control of the fish pathogen koi herpesvirus, or cyprinid herpesvirus 3 (CyHV-3), we have started to identify putative viral envelope and capsid proteins. Recent advances in high-resolution ultrasonography combined with color-coded Doppler analysis have enabled a new insight to be gained into fetal physiology and allowed the investigation of small, previously inaccessible fetal vessels under normal and abnormal conditions.

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A controlled evaluation of a monovalent Shigella vaccine in a highly endemic environment. An initial list of 25 functions with 188 items was formed through literature review.

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We analyze patients with early progression after laparoscopic radical cystectomy in a large cohort by the ESUT (European Association of Urology Section of Uro-Technology). Study 3 showed that agentic and communal individuals used more differentiation and integration to structure memories about social separation and connection, respectively. We used a computerized version of the Morris water task to assess whether this task will generalize into the human domain and to examine whether sex differences exist in this domain of topographical learning and memory. It is also important to pick a person who will be happy in the location and practice, and get along well with other people. A growing body of literature has demonstrated that chronic pain is common for patients with end- stage renal disease (ESRD), is typically moderate or severe, and impacts virtually every aspect of health-related quality of life.

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GC-MS analysis of incenses for possible presence of allergenic nitromusks. Improving stroke prevention in patients with atrial fibrillation. It also increased the area fractions of cytoplasmic vesicles in regenerating endothelium. Glycosylation of agrin with the CT antigen, by contrast, increased agrin binding to myotubes and potentiated its AChR clustering activity at subsaturating concentrations.

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The patient tolerated the operation well and was discharged 28 days post-operatively, but died of liver metastasis 4 months after surgery. While many of the advances in therapeutic pancreatic endoscopy have paralleled the shift of endoscopic ultrasound from a purely diagnostic to therapeutic modality, other new techniques are simply modifications on existing procedures. An analysis of expression of CDK1 and CDK1-associated genes in the NCI60 cell line database confirmed the broad association of these genes with chemotherapeutic responsiveness. Fatty acid amide hydrolase (FAAH), the enzyme responsible for degradation of the endocannabinoid anandamide, has emerged as a promising target for anxiety-related disorders. Intense SSB activity was always associated with the formation of dried pellets.

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Schistosoma japonicum is a major infectious agent of schistosomiasis. Carbohydrate metabolism enzymes of purple sulfur-bacteria during growth in the dark Double waveguide couplers produced by simultaneous femtosecond writing. Forty-eight patients had non-expanding retroperitoneal hematoma and were treated expectantly. capricolum is related evolutionarily to the homologous enzyme from M.

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Prevalence of Hepatitis B virus, Hepatitis C virus and human immunodeficiency virus infections among patients candidate for orthopedic trauma surgeries. Different factors might influence the correct healing of anastomosis, but adequate perfusion of the bowel is highlighted as one of the most important elements. The concentration of glutathione in the rat cerebral cortex, cerebellum and liver was examined during postnatal development. The severity of SVAS is quite variable, both in series of Williams syndrome patients and within SVAS kindreds, suggesting that other genetic factors are involved in expression of the phenotype.

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Apobec-1(-/-)/LDLR(-/-) mice were fed a high-fat diet until they were 24 weeks and were subsequently transferred to chow. Ten of the twenty LGTs are distributed and conserved in all species investigated, while the remainder have been subjected to modifications, or undergone pseudogenization, degradation or loss in one or more species. Sleep Variability Among Older Adults With Insomnia: Associations With Sleep Quality and Cardiometabolic Disease Risk. there was a significant improvement (no long-term medication, only mild pain under unusual strain, minimal medication under such circumstances).

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They selectively enhance or partially mimic certain actions of insulin, causing a slowly generated antihyperglycaemic effect in Type 2 (noninsulin dependent) diabetic patients. L1 induced global changes in the EC transcriptome, altering several regulatory networks that underlie endothelial pathophysiology, including JAK/STAT-mediated pathways. Immunohistochemical staining of survivin and Ki-67 was performed by the standard streptavidin-peroxidase technique on paraffin sections of 55 cases of HCC. Such annotations can have a critical role in identifying putatively causal variants for a disease or trait among the abundant natural variation that occurs at a locus of interest.

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According to Bayesian probabilities of bacteremia, patients in both cohorts were grouped into bacteremia risk groups. People with heart disease should avoid prolonged use of certain anti-inflammatory drugs, Naproxen (Aleve) is safest. Coexpression of icaA with icaD led to a significant increase in activity. In three animals, the ultrastructural finding of intramyelinic vacuolation due to splitting of the myelin lamellae at the intraperiod lines indicated myelin edema. A randomized controlled trial of thymosin-alpha1 versus interferon alfa treatment in patients with hepatitis B e antigen antibody--and hepatitis B virus DNA--positive chronic hepatitis B.

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This study was designed to explore the effects of type I collagen on the expression of inducible nitric oxide synthase (iNOS) in serum-stimulated Raw264.7 cells and to study the molecular mechanistic basis. Novel hepatic microRNAs upregulated in human nonalcoholic fatty liver disease. Anti-hVEGF hairpin ribozyme can effectively inhibit VEGF expression and growth of hepatocarcinoma in vitro and in vivo.

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