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High-performance liquid chromatographic assay for alpha-lipoic acid and five of its metabolites in human plasma and urine. All animals developed deformations of the skull in the sagittal and transversal planes. However, the specific members of the NF-kappa B/Rel transcription factor family involved in the LPS response, and the mechanisms through which LPS-generated signals are transduced remain unclear.

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The effects of FR901228 on the cell cycle, chromatin structure, and histone acetylation were examined and compared with those of TSA. coli excreted in only 2 of 24 urine specimens exhibited mannose-specific adherence, about half of the broth cultures from these specimens did so. Increased concentration of Na,K-pumps in skeletal muscles of patients with chronic obstructive lung disease.

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None of the MAb neutralized LGTV in cell culture assays, but one of the preM-specific MAb protected weanling mice against a virulent LGTV challenge. Angiographic embolisation (AE) is a successful treatment for haemodynamically unstable pelvic ring injuries. The composition of exosomes is not random, suggesting that the incorporation of cargo into them is a regulated process. Understanding and measuring AIDS-related stigma in health care settings: a developing country perspective. The nature of the visual deficit in human amblyopia has been keenly sought over the last decade.

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The presence of this neurotoxic metal in landfills is a concern due to the potential for it to leach or volatilize from the landfill and impact local ecosystems. Associations Between Perceived Weight Status, Body Dissatisfaction, and Self-Objectification on Sexual Sensation Seeking and Sexual Risk Behaviors Among Men Who Have Sex with Men Using Grindr.

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Individuals hospitalized for kidney or ureter stones are at increased risk of developing renal pelvis/ureter or bladder cancer, even beyond 10 years of follow-up. Data collected during baseline assessments and follow-up (maximum of 6.79 years) were obtained. Dysconnectivity in schizophrenia can be understood in terms of dysfunctional integration of a distributed network of brain regions. The results indicated that the SOM had better classification performance than that of a stepwise discriminant analysis over the original data.

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Pathogen solution was prepared in accordance with Technical Standard for Disinfection. The objective of this work was to collect and summarize a detailed historical review of the surgical treatment of pelvic organ prolapse (POP) in which we specifically focused on the anterior compartment. Afatinib is a potent, irreversible, ErbB family blocker in clinical development for the treatment of a variety of solid tumours.

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Two infants with congenital hypotonia were evaluated for limited mouth aperture. The wall of the cavity was characterized by longitudinal folds, which were mushroom-shaped in transverse section. In mitral valve (MV) repair, we adhere to a biological concept of preservation of the native valves and avoidance of any prosthetic materials except for sutures whenever possible. Taken together, these data show that an upregulation of cyclin B1 protein and accumulation of thymocytes at the G2/M phase in MRL-lpr/lpr mice might play an important role in the aberrant development of T cells in these mice. 20 healthy, adult, sexually intact female dogs of various breeds.

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Oxidative stress contributes to soluble fms-like tyrosine kinase-1 induced vascular dysfunction in pregnant rats. A study of the structure of bioceramic coatings obtained by plasma spraying of hydroxyapatites of synthetic and biological origins Although studied extensively, it remains challenging to predict contact map using only sequence information. The incidence and predictor of lymph node metastasis for patients with T1mi breast cancer who underwent axillary dissection and breast irradiation: an institutional analysis.

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The NFI-Regulome Database: A tool for annotation and analysis of control regions of genes regulated by Nuclear Factor I transcription factors. Here, we have established multifunctional nanoparticles (MFNPs) using a single-molecule modification of TPGS, which can deliver a hydrophobic drug, paclitaxel (PTX), and a hydrophilic drug, fluorouracil (5-FU), and overcome MDR in cancer. Cytotoxic effect of ascorbate and its derivatives on cultured malignant and nonmalignant cell lines. Inherited epidermolysis bullosa, which encompasses at least 30 distinctive genetic diseases, may be associated with marked functional impairment, the result of the presence of severe cutaneous and extracutaneous manifestations or complications in some of its subtypes. They are not only important in the immediate posttransplantation period, but perhaps of even greater importance in the long-term management of transplant recipients.

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Opposing trends presented in the proximal trabecular bone, probably because of differences in load transfer when shorter stems are used. Cost of adverse events during treatment with everolimus plus exemestane or single-agent chemotherapy in patients with advanced breast cancer in Western Europe.

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This is the first report of the use of a single-access port to perform transanal endoscopic microsurgery. Results of hematocrits, ultrasound findings, hCG levels, time for hCG levels to reach less than 15 mIU/mL, and outcome were noted. Circadian epigenomic remodeling and hepatic lipogenesis: lessons from HDAC3.

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Multiway principal component analysis is applied to assess the seed quality using routinely gathered plant data. X-ray irradiation induced defects in the commercial soda-lime container glass were studied by means of optical spectrophotometer and ESR. Our findings suggest that mechanisms of cardiotoxicity may shift from a predominantly AHR-independent mode during early weathering to a multiple pathway or synergistic mode with prolonged weathering and increased proportions of dissolved alkyl-PAHs. Medullary thyroid cancer (MTC) is a neuroendocrine tumor that arises from the calcitonin-secreting parafollicular cells of the thyroid gland. Vesicle-associated Membrane Protein 3 (VAMP3) Mediates Constitutive Trafficking of the Renal Co-transporter NKCC2 in Thick Ascending Limbs: ROLE IN RENAL FUNCTION AND BLOOD PRESSURE.

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Thromboembolism is a common concern in ventricular assist device (VAD) therapy. CO2 rapidly diffuses into the cell, where it may result in an excess of hydrogen ions. Changes and effect of PACAP-38 on intestinal ischemia-reperfusion and autotransplantation. Our results, together with previous studies showing beneficial effects of the extracts obtained from C.

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Gas chromatography/olfactometry, gas chromatography, and multidimensional gas chromatogaphy/mass spectrometry techniques were used to investigate the most important odorants of grapes diseased by powdery mildew. Semen was collected with an artificial vagina from four adult rams. Studying prevalent cases of periodontitis underestimates the association between incidence periodontitis and CHD. Anti phospholipid antibody (APA), of both IgG and IgM class, was assayed in plasma obtained from patients with autoimmune haemolytic anaemia (AHA) and active haemolysis. The qualitative method Interpretative Phenomenological Analysis (IPA) was used.

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Escalation therapy with bortezomib, dexamethasone and bendamustine for patients with relapsed or refractory multiple myeloma. Data were collected from April 2006 to September 2007 for patients treated with caspofungin for a single episode of IA. The present study aimed to cross-validate normal as well as abnormal in utero tractography results of commissural and internal capsule fibers in human fetal brains using postmortem histological structure tensor (ST) analysis.

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A double-blind, randomized, parallel-group, multicentre design was employed. Although substantial medical resources are utilized in the treatment of psoriasis, the majority of affected persons make less than one visit per year to a physician for treatment.

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Monitoring of stimulated cycles in assisted reproduction (IVF and ICSI). Moreover, P-glycoprotein transports various endogenous substrates such as cytokines and chemokines involved in inflammation, and may thereby affect the risk of malignity. Effect of heparin on myocardial contractility of the dog and on Na, K-ATPase. Prevalence of antibodies to the hepatitis C virus among Arab and Chaldean Americans in southeast Michigan, USA.

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The outcomes assessed included time to diet, hospital length of stay (LOS), biliary drainage procedures, morbidity, and mortality. This study was designed to examine the effect of atorvastatin on homocysteine (Hcy)-induced activation of ER stress and the potential mechanisms regarding AMP-activated protein kinase (AMPK).

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Performance, characteristics, and case mix in Japanese and American teaching hospitals. Mutations in the mineralocorticoid receptor gene cause autosomal dominant pseudohypoaldosteronism type I. Precancerous isolates possessed a higher number of motifs, and precancerous strains from Nashville induced higher levels of IL-8 than Colombian strains.

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An exploration of the expression of MK and MVD in cervical cancer tissues before and after NACT QCT is more sensitive than DXA to discriminate vertebral collapse. We randomly assigned healthy and mature beagles to one of four groups. Current needs for human and medical genomics research infrastructure in low and middle income countries.

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Further, the specificity of these effects to depression is unknown. We have developed a microdissection technique which allows to selectively procure and genetically analyze small populations of neoplastic cells from the glass slide. Significance of AG in OSAHS operation treatment guidance and evaluation of postoperative efficacy Morphologic classification and problems of the pathogenesis of brain abscess This study aimed to understand the influences and decisions of households with children with asthma regarding keeping warm and well at home in winter.

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Early diagnosis and treatment of this entity are crucial because it affects relatively young individuals, and treatment options for advanced disease are limited. To review the literature of congenital hairy polyps and describe the clinical presentation, operative management, and histologic findings of a congenital hairy polyp arising from the palatopharyngeus muscle in a neonate with recurrent choking episodes. Changes may be seen even in patients with little clinical evidence of corticomotoneuron deficit. For the random bond Potts model, we have obtained accurate numerical estimates for the critical exponents and demonstrated that the density profiles are well described by conformal formulas.

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A hemodialysis unit was established at a rural summer camp for children. The ratios of kidney injury markers to urinary Cr were used for comparisons.

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It is believed that neutrophilic hypersegmentation can be a valuable adjunct in documenting and/or uncovering incipient folate deficiency. Impact of different surgical and postoperative adjuvant treatment modalities on survival of sinonasal malignant melanoma. Ketoconazole (Keto) is an antifungal agent that also inhibits the synthesis of adrenocorticosteroids and has been reported to act as a glucocorticoid receptor antagonist. Peripheral lung tissue, small and large pulmonary arteries, airways, and isolated vascular smooth muscle cells from small pulmonary arteries produced 20-HETE when incubated with AA. This 23-kDa protein had the same biological activity as hIL-11 in a mouse plasmacytoma, T1165.

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Here, we demonstrated that nano-TiO2 can significantly degrade the production of NO in LPS-induced RAW264.7 mouse macrophages. Gold nanoparticle seeds were covered by a thin liquid layer containing precursor solution. We have investigated Hsc66 substrate specificity using phage display and a peptide array of IscU.