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Lastin (Azelastine)
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Azelastine

Lastin, sold under the brand name Optivar among others, is a medication primarily used as a nasal spray to treat allergic rhinitis (hay fever) and as eye drops for allergic conjunctivitis. Other uses may include asthma and skin rashes for which it is taken by mouth. Onset of effects is within minutes when used in the eyes and within an hour when used in the nose. Effects last for up to 12 hours. Common side effects include headache, sleepiness, change in taste, and sore throat. It is unclear if use is safe during pregnancy or breastfeeding. It is a second-generation antihistamine and works by blocking the release of a number of inflammatory mediators including histamine. Lastin was patented in 1971 and came into medical use in 1986. It is available as a generic medication. A 22 millilitre bottle in the United Kingdom costs the NHS about £10.50 as of 2019. In the United States the wholesale cost of this amount is about US$8.40. In 2016 it was the 267th most prescribed medication in the United States with more than a million prescriptions.

Other names for this medication:
Azelastine, Afluon, Allergodil, Astelin, Astepro, Asthafen, Azel, Azelastin, Azelastina, Azelone, Azen, Azep, Azeptin, Ketasma, Lastin, Optilast, Optivar, Otrivine, Phenergan, Rhinolast, Rinalin, Xanaes,

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Post-arthroscopic glenohumeral chondrolysis is a devastating and rapidly evolving condition that most often strikes young patients. Association between estimated glomerular filtration rate and clinical outcomes in patients with acute ischaemic stroke: results from China National Stroke Registry. At 1 month after resolution of posttraumatic amnesia, written language production in children with TBI is negatively correlated with severity of injury.

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Exciton interaction in a bacteriochlorophyll--protein from Chloropseudomonas ethylica. Health professions in the cantons of Vaud and Fribourg: growth, regional inequalities and interprofessional equilibrium Five groups of experiments were performed to study the effect of pulsed-dye laser irradiation delivered through a 320 microns core ball-tip fiber into the femoral artery. Pediatric presumptive PTB cases (both TB and Drug Resistant TB (DR-TB)) accessing any public health facilities in study area were prospectively enrolled and tested on Xpert MTB/RIF following a standardized diagnostic algorithm. Furthermore the way we synthesized the drug to get hold of it in a pure form is described.

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Sediment porewater extraction and analysis combining filter tube samplers and capillary electrophoresis. The practical value of roentgenograms of the region of the temporomandibular joint Correlation between auditory function and internal auditory canal pressure in patients with vestibular schwannomas. A mechanical description is presented of the growth of a tumor and the resulting deformations of surrounding normal tissue.

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This study aims to demonstrate that cartilage nanoindentation modulus is a highly sensitive indicator of the onset and spatiotemporal progression of post-traumatic osteoarthritis (PTOA) in murine models. Although the exact mechanism for how probiotics may aid in the reduction of symptoms commonly found in IBS is unknown, the effects of probiotics on alterations in gut bacteria appear to play a part.

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A recombinant Hsp30 protein was produced and tested preliminarily for its immunoreactivity with sera from P. Compared to the baseline condition, all countermeasures improved intramodal tactile change detection. Immunolocalization of Arthropsin in the Onychophoran Euperipatoides rowelli (Peripatopsidae). To investigate the individual and combined effects of allopurinol and hyperbaric oxygen (HBO) therapy on biochemical and histopathological changes, oxidative stress, and bacterial translocation (BT) in the experimental rat acute pancreatitis (AP). A soybean cyst nematode sex pheromone (vanillic acid), chemical analogs of the pheromone, and the fungus Verticillium lecanii were applied in alginate prills (340 kg/ha) to microplots and small-scale field plots as potential management agents for Heterodera glycines on soybean.

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A 42-year-old male patient with a long-standing evolution of chronic pancreatitis and 8-year long evolution of pancreas pseudocyst was referred to the Military Medical Academy, Belgrade due to worsening of the general condition. Cholesterol synthesis inhibitors (HMG-CoA Reductase Inhibitors) are reported to decrease cholesterol saturation index of duodenal bile in hypercholesterolaemic subjects. Cumulative PA was defined as long-term active versus long-term inactive. The success of gene therapy will depend, in part, on insight into the factors summarized here, very much like successful drug therapy has depended on an understanding of the manifold influences of pharmacokinetics and pharmacodynamics.

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