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Forty-six male adults rats, weighing approximately 200 g at the beginning of the experiment, were distributed into five groups-four experimental and one control. Utilization of radiation therapy in Norway after the implementation of the national cancer plan--a national, population-based study.

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Fragment 3 caused the most vigorous response by cells from mice immunized yeasts, and fragment 1 caused the most vigorous response by cells from mice immunized with rhsp60. To ensure exact determination of the activity used, dose calibrators were checked using (68)Ge standards. Operating time, blood loss, length of skin incision, and postoperative hospital stay and complications were examined using the operation records and medical charts. Dopaminergic terminals in the nucleus accumbens but not the dorsal striatum corelease glutamate. Immunohistochemical distribution of dynorphin B in rat brain: relation to dynorphin A and alpha-neo-endorphin systems.

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The aim of the project was to provide support to the hospital supervisors in order to improve the overall quality of hospital posts in GPST programmes and their relevance to General Practice training, and to provide guidance to GP trainees to target their learning most effectively within each specialty post to improve relevance to future career. Ultrasound-induced cavitation in tissue and organs has been well recognized and documented. Although chloride-rich fluids are associated with AKI based on observational studies, direct proof of harm is lacking.

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This study revealed that the drug is associated with larger increases in postoperative alveolar-arterial oxygen gradient and shunt and prolonged tracheal extubation time in patients undergoing coronary artery bypass grafting, which indicate that use of the drug may hinder early tracheal extubation. Orbital exenteration is a surgical procedure that results in devastating functional and aesthetic losses. Clinical and pathological features as well as biochemical outcomes were compared between the groups.

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We acquired high-resolution structural images from the brains of 14 men, 14 women, who did not use, and 14 women, who did use hormonal contraceptives. Epigastric vessels were safely cut and coagulated using the thulium laser. Patients with coexistent contralateral limb-threatening ischemia at the time of initial ipsilateral operation were excluded, as were patients with bilateral disease who underwent a staged contralateral procedure within 3 months of the ipsilateral operation. Isolated atrial amyloidosis: a clinicopathologic study indicating increased prevalence in chronic heart disease.

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Recent studies have shown that fasudil, a selective ROCK inhibitor, may play a pivotal role in a number of pathological conditions, ranging from cardiovascular diseases to pulmonary hypertension and erectile dysfunction. We used freeze fracture and cytochemical techniques to provide evidence for change in membrane structure and the activity of membrane pumps after nondisruptive axonal injury in the adult guinea pig optic nerve. Doppler echocardiography is found to be a gold standard key to confirm acute rheumatic heart disease and ARF.

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With regard to the cleaning ability of root canals, there were no significant differences between the K-file and Mtwo rotary system in primary and permanent teeth in the apical, middle or coronal third of the canals. Experimental Measurement of the Static Coefficient of Friction at the Ti-Ti Taper Connection in Total Hip Arthroplasty. Optimization studies (of growth factor and matrix) indicate multiple suitable combinations and suggest both a most robust and a minimal system. Correlations of skinfold thicknesses and circumferences at exactly defined body sites with leptin in 10-12-year-old boys with different BMIs. To achieve low excess loss fiber couplers, analysis on mode coupling behavior in fused fiber couplers has been carried out using a combination of a scalar wave finite element method and a step approximation method, with an emphasis on clarifying the excess loss mechanism in fused polarization-maintaining (PANDA) fiber couplers.

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Effect of hydrogen sulfide on oxidative stress in hypoxic pulmonary hypertension In the light of a biology-based model of breast cancer metastasis development, IBTR peak delay most likely originates in a more prolonged dormancy time that, in turn, is related to local microenvironment conditions.

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However, major uncertainties remain due to use of variable and non-validated methods. Groups were tasked with configuring a research topic into a research project.

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Assessment of bile and serum mucin5AC in cholangiocarcinoma: diagnostic performance and biologic significance. Children with cystic fibrosis were well able to metabolize serotonin taken by mouth. The Limitations of Using a National Database to Investigate Risk Factors for Venous Thromboembolism. Clinicoimmunological and bronchological examination was performed in 452 patients with bronchial asthma (BA) which were divided into two groups: 286 patients with late BA (onset at the age of 40 and older) and 166 patients with BA onset at the age under 40.

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An ultrasound examination of the uterine cavity showed presence of an enlarged polypoid mass. Besides the well-known risk factors, Epstein-Barr virus (EBV) might play a significant role in oral squamous cell carcinoma (OSCC). Implications of stability in factor pattern and structure for further BIB development and for utilization in the framework of a longitudinal study are discussed. Genes from pUM505 plasmid contribute to Pseudomonas aeruginosa virulence. Therapies aimed at the cellular level of the disease are currently not available.

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Symptomatic slow-acting drugs (chondroprotectors) as different dosage forms have widespread application in the treatment of osteoarthrosis (OA) at different locations. Radiographic evaluation of the hands and feet was performed at 0 and 24 months. Analysis and feasibility were performed in 42 arteries of 36 patients. Diffusion-weighted imaging showed increased apparent diffusion coefficient, representing vasogenic edema.

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This study aimed to investigate the effects of active vitamin D on serum lipids and oxidative stress markers in type 2 diabetic patients. The purpose of this study was to determine the association of HDL particle concentration (HDL-P) and HDL subclasses with mortality in a high-risk cardiovascular population and to examine the clinical utility of these parameters in mortality risk discrimination and reclassification models.

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The R260W mutation was identified in two families with MWS and in two families with FCU, of different ethnic origins, thereby demonstrating that a single CIAS1 mutation may cause both syndromes. Better antidepressant responders had increased, whereas poorer responders had a decreased left subgenual ACC and hippocampal metabolism. A recent emphasis on the morbidity of ICBG has helped to fuel the costly growth in clinical use of alternatives, such as bone morphogenetic protein-2. We sought to elucidate whether AASI is associated with baroreflex sensitivity (BRS) or blood pressure (BP) reactivity to stress in individuals with cardiovascular risk.

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From the measurements of the fringe visibilities and the fringe shifts on discrete planes, the spatial irradiance distribution of the illuminating source which is separable in two orthogonal directions can be synthesized. Our aim was to describe the effect over 48 hours of cinacalcet in hemodialysis patients with controlled secondary hyperparathyroidism. Efficacy of Cancer Care Communication Between Clinicians and Latino Patients in a Rural US-Mexico Border Region: a Qualitative Study of Barriers and Facilitators to Better Communication. Many aspects of the spectrum of the disease and the reservoirs and routes of transmission are still unknown and thus deserve additional research. The aim of this study was to examine the effect of NC on complications following immediate free flap breast reconstruction.

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In this study, we determined which specific subtypes of mAChRs control synaptic input and excitability of medial vestibular nucleus (MVN) neurons that project to the cerebellum. The discovery of these signaling pathways has led to important new insights into their role in lymphocyte maturation, as it has emerged that mutations in the genes encoding both gamma c and JAK3 result in similar forms of severe combined immunodeficiency (SCID). MEK kinase 1 (MEKK1) activates the c-Jun NH2-terminal kinase (JNK) pathway in response to exposure of cells to microtubule toxins, including taxol. Personal space as a predictor of performance under close working conditions.

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All post-2010 isolates possessed common sequence changes in each gene. Our results showing that severely stressed hepatoma cells overexpressed the multidrug resistance gene(s) raise the possibility that the P-glycoprotein may participate in protection against environmental stress such as heat. Cardiovascular and ECG abnormalities were studied following injection of venom of Buthus tamulus, a common scorpion found in South India.

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This could function as a mechanism by which hsp expression is integrated with the control of cell division or other PP2A-regulated pathways. Since the advent of new imaging methods (CT, MRI), plain radiographs still play a central role in the evaluation of the non-traumatic painful hip. The decline in relative viscosity above this may be caused by turbulence in the saline flow. There are no data to indicate that schools which eliminated corporal punishment became any worse. Bioinformatics analyses combined microarray identify the differentially expressed microRNAs in periventricular leukomalacia.

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Although further analysis is required to clarify the influence of overweight on the biological features of ESCC, glucose metabolism may be a therapeutic target for ESCC. Stimulus-bound heart rate decreases were found only at sites in the anterodorsal aspect of the lateral hypothalamus, whereas no changes in heart rate were observed at ventral or posterior sites. Child Support Grant access and receipt among 12-week-old infants in an urban township setting in South Africa. In this study, we eliminated EphA2 expression in 2 transgenic mouse models of mammary carcinoma.

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Three closely related herpesviruses are associated with fibropapillomatosis in marine turtles. The aims of the present study were to determine the incidence of CAP in esophageal cancer patients who underwent radical esophagectomy and to identify the risk factors. Immunological and neuroendocrine responses of rats to prolonged or repeated stress. The role of adjuvant chemotherapy and radiation therapy for this highly malignant rare tumor should be evaluated in a prospective study with precise histological diagnosis.

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Pathomorphological disorders of the nervous system in experimental renal insufficiency In light of the mutually exclusive distributions of these same characters among the crown groups, this result suggests that sponges exhibited an early episode of disparity expansion followed by comparatively constrained evolution, a pattern shared with many other metazoans but obscured by the conventional fossil record of sponges. This inhibition correlated with a blockade in EPO signal transmission specifically via ERK, with preservation of JAK2-STAT5 and Akt activation.

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We show that covalently immobilized signal factors fully retain their biological properties and efficiently promote differentiation of mouse and/or human precursor cells leading to the production of dendritic cells and macrophages. Although enzyme-linked immunosorbent assays (ELISAs) that use virus-like particles (VLPs) have proved useful, the assays have, in general, had moderate sensitivities and low signal-to-noise ratios. The psychosocial impact of urinary incontinence on women aged 25 to 45 years. NAPE-PLD(-/-) mice have greatly reduced brain levels of long-chain saturated NAEs but wild-type levels of polyunsaturated NAEs (e.g., anandamide), suggesting an important role for NAPE-PLD in the biosynthesis of at least a subset of endogenous NAEs in the mammalian nervous system.

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Statistical analysis of these unusual data showed that the observed pattern was independent of the effects of host age or sex, and provided compelling evidence of a marked spatial component of the second phase epidemic. We concluded that multiple wheat MBD genes were present and they might play important roles in wheat growth and development, as well as in the water-stress response. However, the relationship between child abuse exposure and suicide-related outcomes in military personnel relative to civilians is unknown.

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Pharmacological effects on mirror approaching behavior and neurochemical aspects of the telencephalon in the fish, medaka (Oryzias latipes). In this study, we described a NIR heptamethine cyanine dye, IR-780 iodide, with preferential accumulation in multiple tumor cells without the necessity of chemical conjugation. Identification of a trypsin-like serine proteinase domain encoded by ORF 1a of the coronavirus IBV. Here we have investigated aqueous suspensions of non-Brownian graphite particles including different polymers commonly used as thickening agents or binders in paste formulations. We will review the importance of increasing our comprehension of these events, focusing on migration since they enclose a multitude of potential therapeutic targets for autoimmunity.

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Recently, an automated bench-top immunoassay analyzer (AIA-360), designed for analytes in people, became available for veterinary use. Preclinical and clinical studies covering a large range of genetic disorders are currently underway to solve basic issues dealing with gene transfer efficiencies, regulation of gene expression, and potential risks of the use of viral vectors. Our (17)O NMR experimental and computing approach allowed for identification and quantification of the different crystalline phases involved in the weathering mechanism of a sodium phosphate glass, even in small amount.

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Choledochoduodenostomy is less often performed since the advent of ERCP and endoscopic sphincterotomy (ES). Est-1 locus shows independent assortment from linkage group I marker, sex, and linkage group II markers, yellow and ruby, and therefore is assigned to linkage group III. Estradiol favors glucose oxidation in gastrocnemius muscle through modulation of insulin signaling molecules in adult female rats. Analysis of T-cell development in transgenic and gene-deficient mice suggests that the co-receptor function of CD8 is essential for positive selection. Significant responses to both whole PR3 preparations were seen from patient and control groups, and to the alpha-granules from the patient group.

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Therapeutic interventions that improve non functioning but viable myocardial regions may improve significantly global left ventricular function as well as impact left ventricular dysfunction, in which revascularization entails high perioperative morbidity and mortality. Snf1-related protein kinases 2 (SnRK2s) are major positive regulators of drought stress tolerance.

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The role of alpha-toxin of Clostridium perfringens in experimental gas gangrene in guinea pigs. This phenotype is dependent on SifA, a Salmonella virulence factor that requires the SPI-2-encoded type III secretion system for delivery into host cells.

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We have, however, not been able to detect any absorption of amino acids from the caeca, indicating that nitrogen recycling via the amino acid route does not occur. The use of such fusion proteins, which combine small analyte peptides with enzyme labels, can lead to a new approach to improved assays for numerous biomolecules, including peptide pharmaceuticals, neurotransmitters, hormones, cell surface antigens, etc. In patients with a positive tilt result, tilting caused a decrease in low-frequency (LF) and high-frequency (HF) bands, although the LF/HF ratio did not significantly change.

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Similarly, it was noticed that communities became less similar with increasing distance from the shore. Most of the morbidity in the early months after transplantation. We describe a new course, Stem Cells and Society, in which students explore the basic biology of stem cell research and the controversy surrounding it. This series of compounds derives its selectivity from a hydrogen bond with the gatekeeper Thr316 of the enzyme.

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Threshold for the upper normal limit of indexed epicardial fat volume: derivation in a healthy population and validation in an outcome-based study. The convulsions could not be terminated by emergency medical services, resulting in aspiration of gastric contents. Both components have been isolated by Sephadex gel-filtration and DEAE-cellulose chromatography. A gene encoding human gastric signet ring cell carcinoma antigen recognized by HLA-A31-restricted cytotoxic T lymphocytes.

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As a reference, we also found that the Scl-AbIII at both doses significantly decreased bone resorption and increased bone formation and bone volume in a red (hematopoietic) marrow site, the 4th lumber vertebral body (LVB). Only mutational inactivation of both NLS motifs resulted in complete exclusion of the fusion proteins from the nucleus. Our findings suggest that a chronic elevation of CRP, which occurs during systemic inflammation and often in patients with cancer, might contribute to promote cancer development and/or progression by downregulating TRAIL in immune cells.

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Clinical Comparison of Autogenous Bone Graft with and without Plasma Rich in Growth Factors in the Treatment of Grade II Furcation Involvement of Mandibular Molars. Units made up by five, ten, twenty, and forty screens have been assembled and tested according to the protocol suggested by Galletti. Seven patients with bloodstream infections caused by Klebsiella pneumoniae isolates with decreased susceptibility to carbapenems were identified between January and April 2005 in the intensive care units of a hospital in Manhattan. Recording neural activity from the auditory cortex (AC) and medial geniculate body (MGB) simultaneously with electrical stimulations of the basal forebrain (BF) in urethane-anesthetized rats, we investigated state-dependent spontaneous and auditory-evoked activities in the auditory thalamocortical circuit.

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These mutants produced smaller amounts of N-acyl homoserine lactones required for quorum sensing, had lost swarming motility, and had reduced expression of virulence-related hrp genes and the algT gene required for exopolysaccharide production. Patients with migraine without aura and epilepsy were enrolled in this observational study. These facts suggest that zinc is required for PDTC inhibition of NF-kappaB activation.

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Overuse of unnecessary medications in frail older adults with limited life expectancy remains an understudied challenge. This suggests that visual-vestibular conditioning of the yaw axis COR also induced changes in the pitch axis OOR.